During our career as researcher we all learned about a variety of infectious and immune diseases. Unfortunately, the devastating effects of some infectious and immune diseases do not correlate with efforts to control them. In the 2022 symposium we will no longer turn away from diseases that affect millions of people yet remain absent from the global health agenda. Be prepared to discover the biology behind these diseases and discover why these diseases are ignored by the public, what environmental factors drive them and how they should be overcome.